Urine Electrolyte Composition and Diuretic Therapy in Heart Failure

Urine electrolyte composition and diuretic therapy in heart failure: back to the future?

Combined aquaretic and diuretic therapy in acute heart failure

INTRODUCTION Acute heart failure (AHF) is a leading cause of hospitalization and readmission in the US. The present study evaluated maximum diuresis while minimizing electrolyte imbalances, hemodynamic instability, and kidney dysfunction, to achieve a euvolemic state safely in a shorter period of time. METHODS AND RESULTS A protocol of combined therapy with furosemide, metolazone, and spirono...

Diuretic therapy and diuretic resistance in cardiac failure.

s 40 venous capacitance within a few minutes before any with oedema is defined as a clinical state where the braking phenomenon occurs before the therapeutic measurable increase in urinary output can be seen [1,2]. This rapid haemodynamic improvement is goal is reached. thought to be due to the release of vasodilatory prostaglandins [3]. However, in a study in patients with severe oedema, i.v. ...

Hypochloremia and Diuretic Resistance in Heart Failure

The fundamental role of sodium in maintenance of fluid homeostasis and progression of heart failure (HF) has been a central paradigm in medicine for more than a century. As a result, a core treatment principal in HF management has been the avoidance of dietary sodium. However, accumulating evidence ranging from the basic sciences to epidemiological studies has challenged this paradigm, suggesti...

tolvaptan: a novel diuretic in heart failure management

heart failure (hf) is still a major problem worldwide with high morbidity and mortality rates. the recently developed medication for hf is still incapable of reducing its morbidity and mortality, and clinical data supporting the efficacy and safety of its mainstay therapy remain insufficient. arginine-vasopressin (avp) plays important roles in circulatory and water homeostasis, one of which is ...